Posts tagged Fractures

Where is the evidence that osteoporosis causes bone fractures?

0

Question : Where is the evidence that osteoporosis causes bone fractures?
Please refer me to well-controlled, peer-reviewed studies that show:
1) Osteoporosis causes bone fractures.
2) Fosamax and other biophosphonates not only slow down bone density loss or increase bone density, but also prevent fractures.
Thanks.
osteoporosis

Best answer:

Answer by Good
Its common sense if the bones become less massive and deteriorate go on yahoo and do a image seach .The bones of women are 35 % less massive than men so they are more susucpetible to back problems than men so women should really taske it easy on there back.

FDA: drug to treat osteoporosis is not responsible for femoral fractures

0

The U.S. Food and Drug Administration issued a statement, they have no indication of an association between fractures of the femur and oral bisphosphonates – found a type of drug to treat osteoporosis, claims despite the claims otherwise.

According to several reports show an increase in the surface of subtrochanteric femoral fractures atypical women prescribed oral bisphosphonates, the FDA began to investigate drugs for osteoporosis. The fractures occurred just below the hip in the thigh – the largest bone in the human body – an unusual place to enter for a break, after which the investigation.

Bisphosphonates are a type of drug used for osteoporosis

offset the bone loss and prevent fractures in women during menopause. The following medicines are popular oral bisphosphonates:

* Fosamax – Merck and Co />
* Reclast – Novartis AG
* Actonel – Warner Chilcott

The FDA has requested information from manufacturers of oral bisphosphonates in June 2008, but did not find Rick elevated in women with drugs. Despite the obvious connection between the two, the FDA is working with external sources in order to examine the matter further.

bisphosphonates have a controversial history. In 2008, drugs were investigated according to several reports, they linked to an increased risk of cardiovascular complications, although the FDA has since been an indication, not a comprehensive cardiac risk are issued.> Merck is facing about 900 lawsuits claim Fosamax patients permanent damage pine. A federal judge refused to dismiss a complaint in January 2010, Fosamax, which means that the drug was responsible for damages, claiming the lower jaw in a woman in Indiana, the drug for about eight years, took a break.

The manufacturer, Merck, has repeatedly denied any association between Fosamax and ONJ or increased risk of fracture. Ron Rogers, a spokesman for Merck, said that “was linked to clinical trials, Fosamax, with an increased risk of fracture of the skeleton.” Until generic versions was available, Fosamax generated around billion dollars in sales for the company.

Unless stated otherwise, by their doctor, the FDA recommends that patients continue taking their medication. The FDA notified healthcare professionals aware of its potential “possible” atypical trochanteric femoral fractures in patients taking oral bisphosphonates, although action has not yet been decided at this time.


Drugs to treat osteoporosis

Prevent vertebral fractures: What do you know about osteoporosis can hurt you

0

winning logo spine universe

Montclair, NJ (Business Wire) 20 There May 2008

Each year, about 550,000 vertebral fractures, 300,000 hip fractures disadvantages. It is only the number of reported fractures: because spinal fractures can be painless, some people do not realize that their bones are so weak that they become cracked. Although vertebral fractures due to osteoporosis are more common than hip fractures, hips get more hype. spine universe, as part of the National Osteoporosis Awareness and Prevention Month, to spread the word on vertebral fractures. The definitive site for back pain, osteoporosis, spine universe has expanded its information to help you work more people understand the risk of fractures.

aging population, osteoporosis and fractures of the spine should be an American concern. Baby Boomer women should be especially careful, since even the youngest baby boomers are now nearing menopause -. A time when a woman’s risk of vertebral fractures due to osteoporosis dramatically

vertebral fractures in osteoporosis are particularly dangerous because it can affect breathing, your mobility, and even irritate or damage the spinal cord or nerves, “says Dr. Isadore Lieberman, chairman of the Programme Committee of the spine at the Cleveland Clinic in Florida.” Although some fractures can be painless, that cause many chronic pain if the bone does not heal or if the nerves are pinched. Multiple fractures cord can even remove your lung capacity as your spine curves forward and reduces the space required for the lungs. “

induced osteoporosis fractures of the spine have a cost, of course: it is estimated that fractures requiring hospitalization costs approximately € 000 required only the first year. If the offer price to hospitals for the care and supervision, and with so many vertebral fractures annually costs add up quickly.

Osteoporosis is a disease that specifically influence on bone density – bone strength. It literally means “porous bones”. Even healthy bones have holes in them as part of its complex honeycomb design. But for people with osteoporosis, the bone bigger holes, making them more sensitive and break easily. Osteoporosis is most often seen in older people, but it can occur in young as well. Women, particularly post-menopausal women develop osteoporosis more likely, but that does not mean that men can not get it. It is estimated that 80% of the 10 million Americans with osteoporosis are women, which means that 2 million men have osteoporosis.

Fortunately, osteoporosis-related vertebral fractures are preventable. SpineUniverse.com offers extensive, detailed article on osteoporosis of the spine. The following links will help patients understand what they can do about osteoporosis:

to http://www.spineuniverse.com/osteoporosis/condition-center/ spine universe condition osteoporosis center
Learn easy to implement, to the prevention counseling http://www.spineuniverse.com/displayarticle.php/article3518.html
Listen to what have to say, the respected spine surgeon about treatment options http://www.spineuniverse.com/displayarticle.php/article1525.html
be read, why it is important elected http://www.spineuniverse.com/displayarticle.php/article3516.html for osteoporosis
About spine universe

spine universe, one of the most visited places in the spine centered on the website that offers online and offline resources for patients and spine. SpineUniverse.com helps patients and their families understand their back or neck problems with clear and simple explanations on the causes of the problems of the spine and how they can be treated. SpineUniverse.com / professional features an industry-leading library of case studies and resources for teaching. Based on an 80 member Editorial Board of leading spine experts ensures spine universe, that all information presented is trustworthy and of the highest quality.

For more information, please visit www.spineuniverse.com.


>

clear = “all”
Osteoporosis

FDA warns of risk of fractures increases with certain drugs to treat heartburn, acid reflux or ulcers

0

FDA warns increased risk of fractures with certain medications for heartburn, acid reflux or ulcers
Consumers who take certain medications for heartburn, acid reflux, or ulcers should be aware of a possible increased risk of fractures of the hip, wrist, and spine.

Read more on News-Medical-Net

Kyphoplasty, The Latest Treatment For Vertebral Compression Fractures

0

Vertebral compression fractures may occur with major trauma, such as a motorcycle accident, or with something as insignificant as a sneeze, or stepping off of a curb. With a compression fracture, the bone compressed and collapses into itself, similar to squeezing a Styrofoam peanut between your fingers. How much force it takes to cause a compression fracture, depends on the quality of the bone. Elderly women with osteoporosis have frail, thin bones, which are easily crushed. But even the young strong bone of an 18 year old, will collapse if sufficient force is applied. These fractures may also be caused by metastatic disease, and multiple myeloma, which can weaken the bone to the point that it simply collapses. A large majority of these fractures are termed wedge fractures, which refers to the shape of the fractured vertebra. The anterior, or front part of the vertebra, is compressed, and the posterior or back portion maintains its height. But in some cases, when sufficient force is applied, the entire vertebra is flattened. Compression fractures cause the sudden severe pain and disability. The compression fracture itself will generally cause only back pain, focused at the sight of the fracture. Occasionally, when fracture fragments are forced out of place and begin pressing on nerves, there may be buttock and lower extremity pain as well. Historically, the treatment for these fractures has been bed rest, and pain medication. Depending on how stable the fracture was thought to be, sometimes a brace or body cast would be added. Young people were more likely to survive the period of immobility. In the elderly population, with multiple medical problems, there was a high rate of mortality from the immobilization. People often had complications with pneumonia, blood clots, and loss of muscle. In many cases, even though the fracture would heal, people were never able to return to regular activity. In 1998 the first kyphoplasty was performed. This new procedure has been shown to restore the height of the vertebra, and quickly stabilize the fracture. There is almost an immediate reduction in pain making it possible to mobilize patients the day after surgery. Braces or body casts are generally not necessary. This surgery is performed through a tiny 1/2 inch incision. A large needle is threaded precisely into the center of the damaged vertebra, using flouroscopic x-ray guidance. Then a balloon is inserted and inflated in the center of the fracture. This pushes the fracture fragments back out to their original position, re-establishing the dimensions of the vertebra, and correcting any deformity. When the surgeon is satisfied with the shape and height of the vertebra, the balloon is deflated and withdrawn. The void that is left is then filled with methyl methacrylate, which is the same bone cement that is used to glue prosthetic joint replacements in place. Within minutes this hardens and immediately stabilizes the fracture fragments. Most people are up the next day. If their pain is not completely resolved, is greatly improved. They are generally able to return to their normal activities within a few weeks. There are risks with any surgery, but kyphoplasty is minimally invasive and the risks are considered to be very low. It is reported that in up to 10% of cases some methyl methacrylate will extrude outside of the vertebra. In most cases this is harmless and does not cause any problems. The American Academy of Orthopedic Surgeons reports that in 1 case in 10,000 this cement may damage or irritate nerves or the spinal cord. A second surgery may be required to remove the excess cement. The benefits of this procedure are that it greatly shortens the time of pain and disability that people with compression fractures are forced to endure. Because people are mobilized the day after surgery, it greatly reduces the risk of complications associated with prolonged bed rest. When comparing the risks and benefits of using kyphoplasty to treat a vertebral compression fracture. The benefits seem to outweigh the risks, and this procedure may be worth considering. Vertebral compression fractures may occur with major trauma, such as a motorcycle accident, or with something as insignificant as a sneeze, or stepping off of a curb. With a compression fracture, the bone compressed and collapses into itself, similar to squeezing a Styrofoam peanut between your fingers. How much force it takes to cause a compression fracture, depends on the quality of the bone. Elderly women with osteoporosis have frail, thin bones, which are easily crushed. But even the young strong bone of an 18 year old, will collapse if sufficient force is applied. These fractures may also be caused by metastatic disease, and multiple myeloma, which can weaken the bone to the point that it simply collapses. A large majority of these fractures are termed wedge fractures, which refers to the shape of the fractured vertebra. The anterior, or front part of the vertebra, is compressed, and the posterior or back portion maintains its height. But in some cases, when sufficient force is applied, the entire vertebra is flattened. Compression fractures cause the sudden severe pain and disability. The compression fracture itself will generally cause only back pain, focused at the sight of the fracture. Occasionally, when fracture fragments are forced out of place and begin pressing on nerves, there may be buttock and lower extremity pain as well. Historically, the treatment for these fractures has been bed rest, and pain medication. Depending on how stable the fracture was thought to be, sometimes a brace or body cast would be added. Young people were more likely to survive the period of immobility. In the elderly population, with multiple medical problems, there was a high rate of mortality from the immobilization. People often had complications with pneumonia, blood clots, and loss of muscle. In many cases, even though the fracture would heal, people were never able to return to regular activity. In 1998 the first kyphoplasty was performed. This new procedure has been shown to restore the height of the vertebra, and quickly stabilize the fracture. There is almost an immediate reduction in pain making it possible to mobilize patients the day after surgery. Braces or body casts are generally not necessary. This surgery is performed thru a tiny 1/2 inch incision. A large needle is threaded precisely into the center of the damaged vertebra, using flouroscopic x-ray guidance. Then a balloon is inserted and inflated in the center of the fracture. This pushes the fracture fragments back out to their original position, re-establishing the dimensions of the vertebra, and correcting any deformity. When the surgeon is satisfied with the shape and height of the vertebra, the balloon is deflated and withdrawn. The void that is left is then filled with methyl methacrylate, which is the same bone cement that is used to glue prosthetic joint replacements in place. Within minutes this hardens and immediately stabilizes the fracture fragments. Most people are up the next day. If their pain is not completely resolved, is greatly improved. They are generally able to return to their normal activities within a few weeks. There are risks with any surgery, but kyphoplasty is minimally invasive and the risks are considered to be very low. It is reported that in up to 10% of cases some methyl methacrylate will extrude outside of the vertebra. In most cases this is harmless and does not cause any problems. The American Academy of Orthopedic Surgeons reports that in 1 case in 10,000 this cement may damage or irritate nerves or the spinal cord. A second surgery may be required to remove the excess cement. The benefits of this procedure are that it greatly shortens the time of pain and disability that people with compression fractures are forced to endure. Because people are mobilized the day after surgery, it greatly reduces the risk of complications associated with prolonged bed rest. When comparing the risks and benefits of using kyphoplasty to treat a vertebral compression fracture. The benefits seem to outweigh the risks, and this procedure may be worth considering. David Stevens PA-CLiving with Back Pain

David Stevens is a physician assistant with 12 years experience working with a spine surgeon and he has recently taken a position with a pain management physician. He brings a special perspective to caring for his patients with pain, because he has been living with back pain ever since a motorcycle accident as a teenager crushed two vertebrae in his spine. His website at Living with Back Pain provides information and inspiration for people living with back pain. Learn more about the treatments for back pain at Back Pain Treatments.

Go to Top