Whey protein for cancer, enhances immunity and other health benefits

Studies point

whey, it is assumed an even better protein supplement than previously. Although the health benefits of whey protein have recently been elucidated, the use of whey protein for medicinal purposes since the time of Hippocrates prescribed. In fact, there are two ancient proverbs from the Italian city of Florence that say, “If you drink a healthy and active whey” and “If everyone were raised on whey want to live, doctors are bankruptcy. “

In previous editions, we have the extensive research showing the many potential benefits for the health of chronic whey protein concentrate. Most of these studies have been conducted in the 1980s and early 1990s, and was very persuasive. Scientists have continued their research on whey proteins with even more impressive results. What follows is one of the most current, interesting and useful research on whey proteins.

Whey and Cancer

Other animal studies for carcinogenic chemicals to see what effects whey protein concentrate would have on the prevention or treatment of cancer have been conducted. Scientists fed rats various proteins and then subjected them to the powerful carcinogen dimethylhydrazine.

As in previous studies, the rats were fed whey protein concentrate showed fewer tumors and a common area of reducing tumors (tumor mass index). The researchers found that whey protein offered “considerable protection for the home” more than other proteins, including soy. 1

Even more interesting, in cancer research and in vivo showed whey protein concentrate, whey inhibited the growth of breast cancer cells to low concentrations (Baruchel S. and Vaiu G., Anti Cancer Research, 1996). Finally, and most importantly, a relatively new clinical study in cancer patients showed regression of tumors in patients fed whey protein concentrate at 30 grams per day. 2

Whey and Glutathione

This new research using whey protein concentrate, researchers conducted a surprising discovery about the relationship between cancer cells concentrate glutathione (GSH) and whey protein. It was found that whey protein concentrate used selectively cancer cells of their glutathione, making them more sensitive to treatments against cancer such as radiation and chemotherapy.

It was found that cancer cells and normal cells respond differently to nutrients and drugs that affect glutathione status. What is particularly interesting to note is the fact that the concentration of glutathione in tumor cells is higher than that of normal cells, which surrounds it. This difference in glutathione status between normal cells and cancer cells is probably an important factor in cancer cells resistant to chemotherapy.

How the researchers said, “tumor cell GSH concentration on the determinants of the cytotoxicity [] toxic to cells in many chemotherapeutic agents and radiation, and an increase in GSH concentration appears at least one of the mechanisms of acquired drug are resistant to chemotherapy. “

They further state “It is known that rapid GSH synthesis in tumor cells is associated with high cell proliferation. Depletion of GSH in vivo tumor decreases the rate of cell proliferation and inhibits cancer growth.”

The problem is that it is difficult to reduce glutathione sufficiently in tumor cells without compromising normal tissue and putting the cancer patient in a worse state. What we need is a compound that can selectively reducing the cancer cells of their glutathione, while increasing or at least maintain the level of glutathione in healthy cells.

This is exactly what whey protein appears to do. In this new research has found that cancer cells were subjected to whey proteins, glutathione is depleted, and inhibits their growth, while normal cells had an increase of GSH and increased cellular growth.

These effects were not observed with other proteins. Not surprisingly, the researchers concluded, “Selective depletion of tumor GSH may in fact cancer cells more sensitive to the effects of chemotherapy and eventually protect normal tissues against the harmful effects of chemotherapy.” The exact mechanism by which whey protein achieves this is not entirely understood, but it seems that the feedback mechanism and regulation of glutathione interferes with normal cell cancerous.

It is known that glutathione production is negatively inhibited by its own synthesis. As a starting value that glutathione levels are higher in cancer cells than normal cells, it is probably easier to reach the level of negative feedback inhibition in the levels of glutathione in cancer cells levels glutathione levels in normal cells.

Whey and LDL-cholesterol

The positive benefits for the health of whey protein concentrate, not with their effects on immunity and cancer prevention and treatment to stop. whey protein concentrate was found that a potent inhibitor of cholesterol oxidized low density lipoprotein. Recent studies show that leads to the conversion of LDL to oxidation of LDL which triggers atherosclerosis. . . plaque and lesions associated with atherosclerosis.

Therefore, any substance that prevents oxidation of LDL thoughts on anti-atherogenic. Although animal protein traditionally been involved as a pro-atherogenic, whey proteins appear to be an exception to the rule. Whey protein consists of several small and large groups, as prepared, for example, beta-lactoglobulin, alpha-lactalbumin, albumin, immunoglobulins and lactoferrin. It was noted that the auxiliary prevent the ability of whey protein concentrate to oxidation of LDL appears to be responsible for the lactoferrin fraction of the protein. 3

Lactoferrin in whey

When the lactoferrin was removed from the protein’s ability to concentrate whey proteins in the oxidation of LDL was reduced to avoid speculating on what the researchers: “Our results suggest that LF (lactoferrin) is the factor more important for the inhibitory effect of whey protein (LDL) and may work synergistically with other factors in the whey protein such as alpha-lactalbumin. “


Another study using rats examined the effects of whey protein concentrate and casein on cholesterol and the risk factors for heart disease. Although casein (milk proteins are more often used in research) is known to increase cholesterol levels in humans and animals has, whey protein has the opposite effect of leading the researchers, “At the level of protein intake [300 grams per kilogram of feed], whey protein significantly reduced plasma cholesterol and hepatic triglycerides and plasma. “4

The hypocholesterolemic effect of whey protein in this study was to focus also associated with a reduction in LDL cholesterol. Of particular interest was the fact that this effect was not observed in cholesterol when animals mixtures of amino acids were fed whey protein that simulated, it is clear that the properties in the whey that effects are beyond its amino acid profile.

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Finally, whey protein appears to play a direct role in bone growth. The researchers found that rats fed whey protein concentrate, increased bone density and bone proteins such as collagen. This discovery led research to determine whether or not whey protein directly osteoblasts (bone cells) stimulates growth in vitro.

Whey protein has stimulated dose-dependent synthesis of total protein, DNA content, and increased hydroxyproline contents of bone cells. 5

It should be noted that all whey protein concentrates are created equal. Processing whey protein, lactose and fat, no need to withdraw their biological activity, special attention by the manufacturer. The protein is at low temperature and under conditions of low acid content is converted to denature “and not” of the protein. Conservation of the natural state of the protein is essential for their biological activity.

These results, combined with the previous decade of study on whey protein, should convince anyone that whey protein concentrate is truly life-extension protein.

Higher levels of glutathione and whey

A decade and a half of conclusions about the benefits of whey protein are profound.

Previous studies:

* Whey protein concentrate significantly increased the levels of glutathione. Glutathione is an essential antioxidant soluble in water in the body that protects cells and serves as a primary detoxifier of harmful substances such as peroxides, heavy metals, carcinogens and other toxins.

* Glutathione is also closely related to immunity, and reduced levels of glutathione in diseases such as AIDS, atherosclerosis, Alzheimer’s and Parkinson’s, put together, just to name a few . In fact, glutathione levels appear to modulate immunity in some way. 6

* Whey protein concentrate was found to consistently raise this extremely important immune stimulant and antioxidant, which examined all of the proteins (including soybeans) higher than normal in several animal studies. 7

A small pilot study of men infected with HIV, whey protein concentrate showed a dramatic increase in glutathione levels of all study participants were fed two of three men reaching their ideal weight. 8

In fact, there are several U.S. and international patents for the treatment of AIDS and the immunity granted to the improvement of whey protein concentrates have been.

* Whey protein improves immune function and fights infections. Animals fed whey protein concentrate consistently dramatic improvement in the humoral and cellular to a variety of challenges are protected, such as Salmonella, Streptococcus pneumoniae 9 and extreme cancer-causing chemicals. This effect was not seen on the immunity to other proteins.

* Whey protein concentrate against cancer. Animals fed whey protein.

References

First /> (And McIntosh GH al. Journal of Nutrition, 1995) 2nd (/> RS Kennedy, GP Konok, G. Bounous, S. Baruchel, TD Lee, oncology research, 1995 3rd (M. Kajikawa et al. Biochemica et Biophysica Acta, 1994)
4th (X. Zhang and AC Beyne Brit. J. Nutri. 1993
)
5th (Y. Takada, AOE S., Kumegawa M., Biochemical Research Communications, 1996)
6th (Rosanne K. and Min Fu Tsan Fidelus. Cellular Immunology, 1986)
7th (Clin G. Bounous and P. Gold. Invest. Med 1991)
8th (G. Bounous, S. Baruchel, J. Faiutz, P. Gold, Clin. Invest. Med 1992)
9th (G. Bounous, Konshavn P., Gold P., Clin. Invest. Med 1988)