Alzheimer’s disease is a progressive, irreversible disease of the brain. Alzheimer’s disease (AD) is the most common form of dementia in the elderly. Alzheimer’s destroys a person’s memory and ability to learn, reason, make, judgments, communicate and carry out daily activities. Genetic factors are suspected, and dominant mutations in three genes identified so for a much smaller number of cases of familial, early-onset AD. People with dementia often have problems thinking and speaking clearly, to remember recent events and learn new things. Over time it is for them to cope with everyday activities and take care of itself hard. Age is the most important risk factor for AD, the number of people with the disease doubles every 5 years to 65 years. Three genes have been discovered that cause early-onset (familial) AD. Other genetic mutations, the excessive accumulation of amyloid protein are associated with age-related causes (sporadic) AD. AD is part of an immune response, that the attempt is to contain the disease. The former can to prevent the likelihood, since studies show that anti-inflammatory drugs may or delay development of AD.

Alzheimer’s progress at very different rates. Family history is another risk factor for Alzheimer’s disease. Multiple risk genes may interact with each other and with non-genetic factors to cause the disease. Cardiovascular Risk Factors The same factors that increase the risk for heart disease and stroke, such as high blood pressure can increase, the risk for late-onset AD. Most people with mild forgetfulness do not have AD. In the early stages of AD can people have trouble remembering recent events, activities, or the names of known persons or property. Oxidative damage related to cell damage by excess free radicals, highly reactive chemicals that may result. Free radicals are often formed as a by-product of metabolism or chemical processes in the cell. Excess free radicals can have a significant neuronal damage, contributing to the development of AD. Type 2 diabetes. A connection between Alzheimer’s disease and type 2 diabetes, the form of diabetes in insulin levels high. One theory is that too much insulin in the blood, inflammation and oxidative damage in the brain, promotes both contribute to AD development.

Symptoms of AD memory loss, language deterioration, impaired ability to mentally manipulate visual information, poor discernment, confusion, agitation and mood swings. Alzheimer’s disease may also behavioral changes such as outbursts of violence or excessive passivity in people who have no history of such behavior. In the later stages of deterioration is the muscle and agility, leading to bedfastness, the inability to feed oneself, and incontinence, to be seen whether the death of intervention by some external cause (eg heart attack or pneumonia) does not. Moderate-to disease progression to the middle of the stage, the patient may still be able to perform tasks independently, but may need assistance with more complicated activities. Severe – As the disease progresses from the middle to late stage, the patient is certainly not in a position to need to carry out even the simplest tasks on their own and constant supervision. You can even lose the ability to walk or eat without help. They would forget to eat and starve.

The treatment of Alzheimer’s disease Tips

1st Acetylcholinesterase (AChE) inhibitors reduce the rate at which acetylcholine (ACh) is reduced and thus the concentration of acetylcholine in the brain (fight the loss of ACh by the death of neurons cholinergin).

2nd Ginkgo for the treatment of cognitive impairment and dementia “, a Cochrane Review concludes that” there is promising evidence of improvement in the perception and function associated with ginkgo After that review, two randomized controlled trials on Alzheimer’s patients it was both showed a significant improvement in these areas.

3rd Tramiprosate (3APS or Alzhemed) is a GAG-mimetic molecule, presumably by preventing the binding of soluble amyloid-beta to the accumulation of the toxic plaques to act.

4th R-flurbiprofen (MPC-7869) is a gamma-secretase modulator sometimes a selective reduction of amyloid-beta 42 agents. It is assumed that the production of toxic amyloid-beta to decrease in favor of the shorter forms of the peptide.

Fifth Leuprolide has also been investigated for Alzheimer’s disease. It is believed by reducing leutenizing hormone levels will be the damage in the brain can work as one ages.

6th Antihistamine drug Dimebon has been found recently to positive effect against Alzheimer’s in preliminary tests show

7th Vaccines or immunotherapy for Alzheimer Unlike typical vaccines, would be used to treat, to diagnose patients, rather than for prevention.

8th Proposed alternative treatments for Alzheimer’s include a range of herbal compounds and dietary supplements.

9th Cognitive and behavioral interventions and rehabilitation strategies can be used as complement to pharmacological treatment, especially in the early to moderately advanced stages of disease used.

10th DNA-based therapy is the treatment of Alzheimer’s disease.