San Diego (Vocus) 4 October 2010

The results are significant, more than 2 million U.S. patients annually undergo an angiogram. The study is published 5th October 2010 in the Annals of Internal Medicine, the journal of the American College of

to be doctors.

doctors are often in the diagnosis of obstructive coronary artery disease, which is made from fat accumulation of cholesterol in the arteries that supply the heart muscle results in question. After the evaluation of a patient? S health and symptoms, doctors usually with stress testing. If these are successful, they can order angiograms, in which a thin tube is threaded to the heart and dye injected to check the blocked arteries.


Scripps

results follow a study published earlier this year in the New England Journal of Medicine, who find that subject in the 400,000 patients without known heart disease who undergo elective angiography, 62 percent didnâ? t have evidence of significant barriers. This study, sponsored by the American College of Cardiology recommended that doctors should do more to determine which patients should have angiography.

the principal investigator, Dr. Eric Topol, director of STSI participated, independent validation study of 526 non-diabetic patients in hospitals in the United States, 39 including Scripps Green Hospital in La Jolla, California’s two-year study analyzed the results of a test expression of genes, cells have investigated the patientsa? Blood and then compared with the results of angiography.

The crucial question we addressed -???? the expression of genes of white blood cells provide information about coronary blockages? – Answered and validated in a cohort of the selection, and angiography, â? Dr. Topol said. â? The results may help our future ability to coronary angiography in patients with true> need.â direct clinical ????

The study was conducted jointly by leading scientific research organizations in the United States, including STSI, Duke University, wrote Vanderbilt Heart and Vascular Institute, Minneapolis Heart Institute Foundation, Piedmont Heart Institute, Washington Hospital Center, Oklahoma Cardiovascular Research Foundation, Cleveland Clinic Foundation and Cardiovascular Research

New York.

The study was funded jointly by CardioDX, a cardiovascular diagnostic company posted Genomics. Independent confirmation of the statistical study was conducted by STSI without funding from the promoter.

Scripps Health

philanthropist 1924 by Ellen Browning Scripps, a nonprofit Scripps Health Community Health billion based in San Diego, Calif. Scripps treats a half-million patients annually through the use of 2,600 affiliated physicians and 12,700 employees among its five acute care hospital campuses, services , home care, and a network of outpatient clinics and 19 outpatient centers and clinics. Recognized as a leader in the prevention, diagnosis and treatment of disease, Scripps is also at the forefront of clinical research and medical education. More information is found under www.scripps.org.


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